TMEM35B

Across TCGA patient cohorts, TMEM35B protein abundance is significantly associated with the protein abundance of many other proteins, with 3,999 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TMEM35B-associated proteins across cancer lineages are H1-2, PPP2R5B_S16, and MNAT1. Each is linked with TMEM35B in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM35B-to-partner and partner-to-TMEM35B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM35B versus H1-2 in GBM, with a Pearson correlation of -0.67.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM35B→partner) and Y-score (partner→TMEM35B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	H1-2 →	-1.273	-0.957	<.001	<.001	3	3
GBM	PPP2R5B_S16 →	+0.508	+0.707	<.001	<.001	3	2
GBM	MNAT1 →	-0.240	-0.591	<.001	.001	3	2
UCEC	RPS2_S77 →	+1.935	+0.595	<.001	.003	3	2
GBM	SF3B1_T267 →	-1.125	-0.724	<.001	<.001	3	2
UCEC	CCDC97_S257 →	+1.274	+0.505	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,999 associations by consensus.

TMEM35B vs H1-2 — GBM

Explore this scatter interactively →