TMEM35A

Across TCGA patient cohorts, TMEM35A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,823 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM35A-associated proteins across cancer lineages are HDGFL3, RNF213, and MATN2. Each is linked with TMEM35A in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM35A-to-partner and partner-to-TMEM35A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM35A versus HDGFL3 in COAD, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM35A→partner) and Y-score (partner→TMEM35A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HDGFL3 →	+0.555	+0.619	<.001	<.001	3	6
PDAC	RNF213 →	-0.430	-0.460	<.001	<.001	3	5
UCEC	MATN2 →	+0.793	+0.670	<.001	.003	3	5
HNSC	CACNA2D1 →	+0.673	+0.531	<.001	<.001	3	5
COAD	DDAH2 →	+0.475	+0.941	<.001	<.001	3	5
CCRCC	MFAP2 →	+0.778	+0.310	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,823 associations by consensus.

TMEM35A vs HDGFL3 — COAD

Explore this scatter interactively →