TMEM30CP

Across TCGA patient cohorts, TMEM30CP mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM30CP-associated genes across cancer lineages are FTH1P14, SNORD114-18, and C9orf57. Each is linked with TMEM30CP in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM30CP-to-partner and partner-to-TMEM30CP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTH1P14 grouped by TMEM30CP-low versus TMEM30CP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM30CP→partner) and Y-score (partner→TMEM30CP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FTH1P14 →	+0.126	+3.884	<.001	.002	3	1
UCEC	SNORD114-18 →	+0.785	+4.299	<.001	<.001	3	1
UCEC	C9orf57 →	+0.142	+3.133	.004	.004	3	1
UCEC	RNU6-440P →	+0.227	+4.464	<.001	.005	3	1
UCEC	GSTA6P →	+0.084	+3.246	.004	.008	3	1
UCEC	RPL23P11 →	+0.128	+2.888	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

FTH1P14 by TMEM30CP expression — UCEC

Explore this box plot interactively →