TMEM30B

Across TCGA patient cohorts, TMEM30B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,957 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM30B-associated proteins across cancer lineages are DNTTIP1, FLI1_S39, and AKNA_S316. Each is linked with TMEM30B in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM30B-to-partner and partner-to-TMEM30B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM30B versus DNTTIP1 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM30B→partner) and Y-score (partner→TMEM30B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DNTTIP1 →	+0.292	+0.677	<.001	<.001	3	5
LSCC	FLI1_S39 →	-0.559	-0.723	<.001	<.001	3	5
HNSC	AKNA_S316 →	-0.558	-0.735	<.001	<.001	3	5
BRCA	AP1M2 →	+0.373	+0.607	<.001	<.001	3	5
UCEC	PTK6 →	+0.748	+0.899	.001	.008	3	4
BRCA	UBR7 →	+0.351	+0.963	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,957 associations by consensus.

TMEM30B vs DNTTIP1 — LSCC

Explore this scatter interactively →