TMEM30B

Across TCGA patient cohorts, TMEM30B protein abundance is significantly associated with the RNA expression of many other genes, with 8,366 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM30B-associated genes across cancer lineages are ATP8B1, GALNT7, and FUT2. Each is linked with TMEM30B in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM30B-to-partner and partner-to-TMEM30B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM30B versus ATP8B1 in OV, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM30B→partner) and Y-score (partner→TMEM30B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ATP8B1 →	+0.869	+0.548	<.001	<.001	3	7
BRCA	GALNT7 →	+1.405	+0.851	<.001	<.001	3	5
LSCC	FUT2 →	+1.264	+0.852	<.001	<.001	3	4
BRCA	BCAS1 →	+1.893	+0.824	<.001	<.001	2	5
CCRCC	TMED10 →	+0.518	+0.696	<.001	<.001	3	4
BRCA	AGR2 →	+2.447	+0.748	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,366 associations by consensus.

TMEM30B vs ATP8B1 — OV

Explore this scatter interactively →