TMEM30B

Across TCGA cell cohorts, TMEM30B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,871 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TMEM30B-associated GO terms across cancer lineages are Desmosome organization, Calcium-independent cell-cell adhesion, and Regulation of potassium ion import. Each is linked with TMEM30B in more than 9 cancer types. Because this analysis shows association rather than direction, both TMEM30B-to-partner and partner-to-TMEM30B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Desmosome organization grouped by TMEM30B-low versus TMEM30B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM30B→partner) and Y-score (partner→TMEM30B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Desmosome organization →	+0.388	+2.523	.001	<.001	3	10
LUNG_SCLC	Calcium-independent cell-cell adhesion →	+0.598	+3.543	<.001	<.001	3	10
LUNG_SCLC	Regulation of potassium ion import →	+0.161	+2.674	<.001	<.001	3	10
STOMACH	Negative regulation of G protein-coupled receptor signaling pathway →	-0.096	-2.468	.001	.003	3	10
STOMACH	Bundle of His cell to Purkinje myocyte communication →	+0.276	+2.482	<.001	<.001	3	9
LUNG_SCLC	Positive regulation of brown fat cell differentiation →	+0.119	+2.185	.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,871 associations by consensus.

Desmosome organization by TMEM30B expression — STOMACH

Explore this box plot interactively →