TMEM30A

Across TCGA cell cohorts, TMEM30A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM30A-associated genes across cancer lineages are REG3G and DIRAS2. Each is linked with TMEM30A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM30A-to-partner and partner-to-TMEM30A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG3G grouped by TMEM30A-low versus TMEM30A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM30A→partner) and Y-score (partner→TMEM30A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	REG3G →	+0.044	+4.867	<.001	.009	3	1
BLOOD_Leukemia	DIRAS2 →	+0.155	+4.087	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

REG3G by TMEM30A expression — BLOOD_Lymphoma

Explore this box plot interactively →