TMEM271

Across TCGA patient cohorts, TMEM271 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,048 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM271-associated proteins across cancer lineages are INPPL1, SCG2, and STMN2_S62. Each is linked with TMEM271 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM271-to-partner and partner-to-TMEM271 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM271 versus INPPL1 in GBM, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM271→partner) and Y-score (partner→TMEM271) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	INPPL1 →	-0.274	-0.912	<.001	<.001	3	3
PDAC	SCG2 →	+0.767	+0.097	<.001	<.001	3	3
GBM	STMN2_S62 →	+0.882	+0.930	<.001	<.001	3	3
COAD	GAP43 →	+1.067	+0.012	<.001	.001	3	3
COAD	GNAO1 →	+0.774	+0.018	<.001	<.001	3	3
GBM	ANK2_S1461 →	+0.551	+0.941	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,048 associations by consensus.

TMEM271 vs INPPL1 — GBM

Explore this scatter interactively →