TMEM270

Across TCGA patient cohorts, TMEM270 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,768 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM270-associated proteins across cancer lineages are RFC2, FXR1, and GINS4. Each is linked with TMEM270 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM270-to-partner and partner-to-TMEM270 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM270 versus RFC2 in LUAD, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM270→partner) and Y-score (partner→TMEM270) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RFC2 →	+0.290	+0.656	<.001	<.001	3	4
LSCC	FXR1 →	+0.291	+0.466	<.001	<.001	3	4
COAD	GINS4 →	+0.687	+0.840	.006	.006	3	4
LUAD	IPO9 →	+0.284	+0.616	<.001	<.001	3	4
LSCC	KIF11 →	+0.648	+0.618	<.001	<.001	3	4
LSCC	MSH2 →	+0.351	+0.446	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,768 associations by consensus.

TMEM270 vs RFC2 — LUAD

Explore this scatter interactively →