TMEM260

Across TCGA patient cohorts, TMEM260 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,457 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM260-associated proteins across cancer lineages are YLPM1, PYCARD, and RPL7. Each is linked with TMEM260 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM260-to-partner and partner-to-TMEM260 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM260 versus YLPM1 in GBM, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM260→partner) and Y-score (partner→TMEM260) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YLPM1 →	+0.313	+0.348	<.001	<.001	3	7
CCRCC	PYCARD →	-0.569	-0.341	<.001	<.001	3	6
GBM	RPL7 →	-0.438	-0.454	<.001	<.001	3	6
PDAC	FKBP3 →	+0.292	+0.345	<.001	<.001	3	6
GBM	POGZ →	+0.217	+0.346	<.001	<.001	3	5
BRCA	PPM1A →	+0.216	+0.456	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,457 associations by consensus.

TMEM260 vs YLPM1 — GBM

Explore this scatter interactively →