TMEM260

Across TCGA patient cohorts, TMEM260 protein abundance is significantly associated with the RNA expression of many other genes, with 4,057 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM260-associated genes across cancer lineages are TMC4, RPL23AP66, and GPANK1. Each is linked with TMEM260 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM260-to-partner and partner-to-TMEM260 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM260 versus TMC4 in COAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM260→partner) and Y-score (partner→TMEM260) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TMC4 →	+1.118	+0.600	.003	.006	3	2
COAD	RPL23AP66 →	+0.760	+0.654	<.001	.006	3	2
UCEC	GPANK1 →	-0.723	-0.296	.001	.009	3	2
OV	ITGB8 →	+1.178	+0.344	.001	<.001	3	2
PDAC	CCDC34 →	-0.693	-0.585	.003	.004	3	2
PDAC	ATG10 →	-0.490	-0.521	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,057 associations by consensus.

TMEM260 vs TMC4 — COAD

Explore this scatter interactively →