Across TCGA patient cohorts, TMEM26 protein abundance is significantly associated with the RNA expression of many other genes, with 7,139 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM26-associated genes across cancer lineages are TMEM26-AS1, GJA1, and DEPDC1P2. Each is linked with TMEM26 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM26-to-partner and partner-to-TMEM26 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM26→partner) and Y-score (partner→TMEM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMEM26-AS1 →	+0.829	+1.705	<.001	<.001	3	4
BRCA	GJA1 →	+2.453	+1.651	<.001	<.001	3	3
LSCC	DEPDC1P2 →	-0.719	-0.696	<.001	.003	3	3
LUAD	DSE →	+1.293	+1.455	.005	.009	3	3
BRCA	SLC35D1 →	+0.917	+1.632	<.001	.001	3	3
LUAD	DNAI4 →	+0.961	+1.156	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,139 associations by consensus.

Exploration

TMEM26 survival (RNA) · tumor vs normal (RNA) · all TMEM26 data types