TMEM259

Across TCGA patient cohorts, TMEM259 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TMEM259-associated genes across cancer lineages are CD4+ Tcm. Each is linked with TMEM259 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM259-to-partner and partner-to-TMEM259 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by TMEM259-low versus TMEM259-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM259→partner) and Y-score (partner→TMEM259) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CD4+ Tcm →	+0.009	+3.648	.007	.017	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tcm by TMEM259 expression — SKCM

Explore this box plot interactively →