Across TCGA patient cohorts, TMEM255B mutation is significantly associated with the RNA expression of many other genes, with 1,908 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM255B-associated genes across cancer lineages are NUDC, GSR, and EFNB3. Each is linked with TMEM255B in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM255B-to-partner and partner-to-TMEM255B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM255B→partner) and Y-score (partner→TMEM255B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NUDC →	+0.410	+2.629	.004	.005	3	4
UCEC	GSR →	+0.709	+2.807	.004	.003	3	3
SKCM	EFNB3 →	-1.280	-3.694	.003	.001	3	3
SKCM	TTF2 →	+0.664	+2.642	.002	.005	3	3
UCEC	PSMC3IP →	+0.738	+3.483	<.001	.002	3	3
UCEC	AOC2 →	+1.208	+2.828	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,908 associations by consensus.

Exploration

TMEM255B survival (RNA) · tumor vs normal (RNA) · all TMEM255B data types