TMEM255A

Across TCGA patient cohorts, TMEM255A protein abundance is significantly associated with the RNA expression of many other genes, with 367 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM255A-associated genes across cancer lineages are GGT1, MYH9, and CAV1. Each is linked with TMEM255A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM255A-to-partner and partner-to-TMEM255A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM255A versus GGT1 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM255A→partner) and Y-score (partner→TMEM255A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GGT1 →	+0.172	+0.491	.002	.002	3	1
GBM	MYH9 →	-0.634	-0.508	.004	.002	3	1
GBM	CAV1 →	-1.844	-0.698	<.001	.001	3	1
GBM	HFE →	-0.447	-0.441	.006	.009	3	1
GBM	DKK1 →	-2.022	-0.528	.003	.004	3	1
GBM	ABCC3 →	-1.476	-0.385	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 367 associations by consensus.

TMEM255A vs GGT1 — GBM

Explore this scatter interactively →