TMEM245

Across TCGA patient cohorts, TMEM245 RNA expression is significantly associated with the RNA expression of many other genes, with 21,351 significant associations in total. THYM shows the largest number of these associations.

The most reproducible TMEM245-associated genes across cancer lineages are SETX, ATE1, and TNKS2. Each is linked with TMEM245 in more than 33 cancer types. Because this analysis shows association rather than direction, both TMEM245-to-partner and partner-to-TMEM245 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM245 versus SETX in UVM, with a Pearson correlation of 0.94.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM245→partner) and Y-score (partner→TMEM245) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	SETX →	+1.566	+1.451	<.001	<.001	3	34
UVM	ATE1 →	+1.769	+1.376	<.001	<.001	3	34
UVM	TNKS2 →	+1.572	+1.426	<.001	<.001	3	34
UVM	TASOR2 →	+1.589	+1.355	<.001	<.001	3	34
UVM	MED13 →	+1.432	+1.356	<.001	<.001	3	34
DLBC	CBL →	+1.624	+0.934	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,351 associations by consensus.

TMEM245 vs SETX — UVM

Explore this scatter interactively →