TMEM244

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM244 mutation is significantly associated with the RNA expression of many other genes, with 638 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM244-associated genes across cancer lineages are RNU1-80P, OR4A5, and RNA5SP161. Each is linked with TMEM244 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM244-to-partner and partner-to-TMEM244 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM244→partner) and Y-score (partner→TMEM244) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNU1-80P →+0.248+4.648<.001<.00132
LUADOR4A5 →+0.084+7.930<.001.00832
UCECRNA5SP161 →+1.267+3.528<.001<.00132
UCECRNU6-741P →+0.384+3.923<.001.00932
UCECPDIA3P2 →+0.533+3.005.001.00132
STADRNA5SP181 →+0.509+5.274<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 638 associations by consensus.

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