Across TCGA patient cohorts, TMEM244 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM244-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tem, and Adipocytes. Each is linked with TMEM244 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM244-to-partner and partner-to-TMEM244 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM244→partner) and Y-score (partner→TMEM244) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.027	+2.260	<.001	.037	3	1
UCEC	CD8+ Tem →	+0.003	+4.606	<.001	.044	3	1
UCEC	Adipocytes →	+0.030	+2.418	<.001	.017	3	1
UCEC	Neurons →	-0.021	-2.300	.026	.036	3	1
UCEC	pDC →	+0.049	+2.815	.045	.036	2	1
UCEC	MEP →	+0.053	+3.470	<.001	.003	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

TMEM244 survival (RNA) · tumor vs normal (RNA) · all TMEM244 data types