TMEM243

Across TCGA patient cohorts, TMEM243 protein abundance is significantly associated with the RNA expression of many other genes, with 2,107 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TMEM243-associated genes across cancer lineages are PMPCB, ALDH3A1, and THG1L. Each is linked with TMEM243 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM243-to-partner and partner-to-TMEM243 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM243 versus PMPCB in OV, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM243→partner) and Y-score (partner→TMEM243) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PMPCB →	+0.663	+0.930	<.001	.001	3	2
OV	ALDH3A1 →	+0.938	+0.760	.003	<.001	3	2
OV	THG1L →	+0.728	+0.615	.002	.005	3	2
OV	PMS2P3 →	+0.617	+0.627	.003	.005	3	2
OV	RBM48 →	+0.606	+0.903	.003	<.001	3	2
OV	TMEM140 →	+0.569	+0.658	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,107 associations by consensus.

TMEM243 vs PMPCB — OV

Explore this scatter interactively →