Across TCGA patient cohorts, TMEM242 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,044 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM242-associated proteins across cancer lineages are ARID1B, MAP3K4, and SCAF8. Each is linked with TMEM242 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM242-to-partner and partner-to-TMEM242 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM242→partner) and Y-score (partner→TMEM242) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARID1B →	+0.231	+0.381	<.001	<.001	3	7
HNSC	MAP3K4 →	+0.356	+0.424	<.001	<.001	3	6
OV	SCAF8 →	+0.237	+0.446	<.001	.002	3	5
BRCA	TMEM70 →	-0.437	-0.317	<.001	.001	3	4
GBM	ACAT2 →	+0.420	+0.372	<.001	<.001	3	4
HNSC	PPIL4 →	+0.269	+0.466	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,044 associations by consensus.

Exploration

TMEM242 survival (RNA) · tumor vs normal (RNA) · all TMEM242 data types