Across TCGA patient cohorts, TMEM242 mutation is significantly associated with the RNA expression of many other genes, with 182 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM242-associated genes across cancer lineages are RNA5SP54, RPL7P53, and FAM138A. Each is linked with TMEM242 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM242-to-partner and partner-to-TMEM242 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM242→partner) and Y-score (partner→TMEM242) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP54 →	+0.467	+7.930	<.001	.008	3	2
SKCM	RPL7P53 →	+0.094	+3.801	<.001	.007	3	1
SKCM	FAM138A →	+0.025	+5.634	<.001	.001	3	1
SKCM	OR7E53P →	+0.083	+4.877	<.001	<.001	3	1
SKCM	RN7SL837P →	+0.108	+5.408	<.001	.002	3	1
SKCM	NPM1P28 →	+0.117	+3.913	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 182 associations by consensus.

Exploration

TMEM242 survival (RNA) · tumor vs normal (RNA) · all TMEM242 data types