TMEM241

Across TCGA patient cohorts, TMEM241 mutation is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM241-associated genes across cancer lineages are TRIM60P3Y, RN7SL201P, and ELOCP18. Each is linked with TMEM241 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM241-to-partner and partner-to-TMEM241 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM60P3Y grouped by TMEM241-low versus TMEM241-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM241→partner) and Y-score (partner→TMEM241) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TRIM60P3Y →	+0.022	+4.408	<.001	.005	3	2
SKCM	RN7SL201P →	+0.133	+3.555	<.001	.004	3	2
BLCA	ELOCP18 →	+0.135	+5.251	<.001	.006	3	1
BLCA	TRBV22-1 →	+0.139	+6.289	<.001	.001	3	1
BLCA	LINC01332 →	+0.111	+5.685	.008	.003	3	1
SKCM	GUCA2A →	+0.105	+3.537	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

TRIM60P3Y by TMEM241 expression — SKCM

Explore this box plot interactively →