Across TCGA patient cohorts, TMEM240 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TMEM240-associated genes across cancer lineages are LCE1E, TRIM51GP, and RNU7-165P. Each is linked with TMEM240 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM240-to-partner and partner-to-TMEM240 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM240→partner) and Y-score (partner→TMEM240) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LCE1E →	+0.404	+3.019	<.001	.005	3	1
COAD	TRIM51GP →	+0.047	+4.332	<.001	.006	3	1
COAD	RNU7-165P →	+0.273	+4.557	<.001	.004	3	1
COAD	CKS1BP5 →	+0.120	+4.332	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

TMEM240 survival (RNA) · tumor vs normal (RNA) · all TMEM240 data types