TMEM238

Across TCGA patient cohorts, TMEM238 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,684 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM238-associated proteins across cancer lineages are LLGL2, AKAP1_T533, and PPP1R18. Each is linked with TMEM238 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM238-to-partner and partner-to-TMEM238 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM238 versus LLGL2 in BRCA, with a Pearson correlation of 0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM238→partner) and Y-score (partner→TMEM238) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LLGL2 →	+0.582	+0.891	<.001	.002	3	5
LUAD	AKAP1_T533 →	+0.417	+0.577	<.001	.003	3	4
CCRCC	PPP1R18 →	-0.271	-0.595	.001	.001	3	4
HNSC	EPCAM →	+1.293	+0.914	<.001	<.001	3	4
HNSC	MYH14 →	+0.778	+0.910	<.001	<.001	3	4
HNSC	RPIA →	+0.344	+0.969	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,684 associations by consensus.

TMEM238 vs LLGL2 — BRCA

Explore this scatter interactively →