TMEM237

Across TCGA patient cohorts, TMEM237 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,344 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM237-associated proteins across cancer lineages are MCM4, MCM5, and MCM6. Each is linked with TMEM237 in more than 7 cancer types. Because this analysis shows association rather than direction, both TMEM237-to-partner and partner-to-TMEM237 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM237 versus MCM4 in LUAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM237→partner) and Y-score (partner→TMEM237) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MCM4 →	+0.723	+0.475	<.001	<.001	3	8
LUAD	MCM5 →	+0.670	+0.458	<.001	<.001	3	8
GBM	MCM6 →	+0.697	+0.475	.003	.002	3	8
LUAD	MCM7 →	+0.669	+0.468	<.001	<.001	3	8
GBM	SF3B3 →	+0.209	+0.441	.001	<.001	3	7
GBM	CDC73 →	+0.339	+0.556	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,344 associations by consensus.

TMEM237 vs MCM4 — LUAD

Explore this scatter interactively →