TMEM236

Across TCGA patient cohorts, TMEM236 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,929 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM236-associated proteins across cancer lineages are MRC1, F13A1, and DOK2. Each is linked with TMEM236 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM236-to-partner and partner-to-TMEM236 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM236 versus MRC1 in GBM, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM236→partner) and Y-score (partner→TMEM236) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MRC1 →	+0.992	+0.373	<.001	<.001	3	9
GBM	F13A1 →	+0.842	+0.259	<.001	<.001	3	8
GBM	DOK2 →	+0.805	+0.340	<.001	<.001	3	7
GBM	FOLR2 →	+1.107	+0.443	<.001	<.001	3	7
OV	VIM_S22 →	+0.642	+0.151	.003	.001	3	7
GBM	ADNP →	-0.336	-0.319	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,929 associations by consensus.

TMEM236 vs MRC1 — GBM

Explore this scatter interactively →