TMEM234

Across TCGA patient cohorts, TMEM234 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,160 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible TMEM234-associated GO terms across cancer lineages are Base-excision repair, Base-excision repair, AP site formation, and Depyrimidination. Each is linked with TMEM234 in more than 24 cancer types. Because this analysis shows association rather than direction, both TMEM234-to-partner and partner-to-TMEM234 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Base-excision repair grouped by TMEM234-low versus TMEM234-high in KIRP.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM234→partner) and Y-score (partner→TMEM234) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	Base-excision repair →	+0.042	+0.813	<.001	<.001	3	25
KIRP	Base-excision repair, AP site formation →	+0.084	+0.982	<.001	<.001	3	23
KIRP	Depyrimidination →	+0.067	+0.851	<.001	<.001	3	22
TGCT	Galactose catabolic process →	+0.071	+0.572	<.001	<.001	3	22
KIRC	Macromolecule deacylation →	+0.038	+0.627	<.001	<.001	3	22
SCLC	Intraciliary anterograde transport →	+0.067	+0.737	.001	<.001	2	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,160 associations by consensus.

Base-excision repair by TMEM234 expression — KIRP

Explore this box plot interactively →