TMEM234

Across TCGA cell cohorts, TMEM234 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,834 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TMEM234-associated GO terms across cancer lineages are Flagellated sperm motility, Golgi to plasma membrane protein transport, and Establishment of protein localization to plasma membrane. Each is linked with TMEM234 in more than 10 cancer types. Because this analysis shows association rather than direction, both TMEM234-to-partner and partner-to-TMEM234 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Flagellated sperm motility grouped by TMEM234-low versus TMEM234-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM234→partner) and Y-score (partner→TMEM234) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Flagellated sperm motility →	-0.115	-0.644	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.181	+1.339	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Establishment of protein localization to plasma membrane →	+0.126	+1.471	<.001	<.001	3	11
STOMACH	Negative regulation of autophagy →	+0.070	+0.982	<.001	<.001	3	11
STOMACH	Vacuole organization →	+0.070	+0.821	<.001	<.001	3	11
LARGE_INTESTINE	Sperm motility →	-0.115	-0.644	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,834 associations by consensus.

Flagellated sperm motility by TMEM234 expression — LARGE_INTESTINE

Explore this box plot interactively →