TMEM229A

Across TCGA cell cohorts, TMEM229A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,363 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM229A-associated GO terms across cancer lineages are Regulation of T-helper 17 type immune response, Intracellular receptor signaling pathway, and Positive regulation of DNA recombination. Each is linked with TMEM229A in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM229A-to-partner and partner-to-TMEM229A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of T-helper 17 type immune response grouped by TMEM229A-low versus TMEM229A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM229A→partner) and Y-score (partner→TMEM229A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of T-helper 17 type immune response →	-0.089	-4.422	<.001	<.001	3	4
BONE	Intracellular receptor signaling pathway →	-0.042	-2.585	<.001	<.001	3	4
BONE	Positive regulation of DNA recombination →	+0.127	+3.312	<.001	<.001	3	4
BONE	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.120	+2.134	<.001	.002	3	3
BONE	Determination of dorsal/ventral asymmetry →	-0.405	-2.854	<.001	<.001	3	3
BONE	Establishment or maintenance of transmembrane electrochemical gradient →	-0.186	-3.288	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,363 associations by consensus.

Regulation of T-helper 17 type immune response by TMEM229A expression — BONE

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