TMEM229A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TMEM229A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM229A-associated genes across cancer lineages are DEFA3. Each is linked with TMEM229A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM229A-to-partner and partner-to-TMEM229A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFA3 grouped by TMEM229A-low versus TMEM229A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM229A→partner) and Y-score (partner→TMEM229A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEDEFA3 →+0.102+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

DEFA3 by TMEM229A expression — LARGE_INTESTINE

Box plot of DEFA3 in TMEM229A-low vs TMEM229A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration