TMEM225B

Across TCGA cell cohorts, TMEM225B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,165 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM225B-associated GO terms across cancer lineages are Positive regulation of stress fiber assembly, Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Vesicle targeting, to, from or within Golgi. Each is linked with TMEM225B in more than 7 cancer types. Because this analysis shows association rather than direction, both TMEM225B-to-partner and partner-to-TMEM225B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stress fiber assembly grouped by TMEM225B-low versus TMEM225B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM225B→partner) and Y-score (partner→TMEM225B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of stress fiber assembly →	+0.100	+0.539	<.001	<.001	3	8
OVARY	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.076	-0.552	.002	.005	3	7
BLOOD_Leukemia	Vesicle targeting, to, from or within Golgi →	+0.048	+0.815	.003	.001	3	7
BONE	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.103	-0.705	.005	.007	2	8
BLOOD_Leukemia	UDP biosynthetic process →	-0.085	-0.770	<.001	<.001	3	7
BLOOD_Leukemia	Pyrimidine ribonucleoside diphosphate biosynthetic process →	-0.085	-0.770	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,165 associations by consensus.

Positive regulation of stress fiber assembly by TMEM225B expression — SOFT_TISSUE

Explore this box plot interactively →