Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, TMEM221 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible TMEM221-associated genes across cancer lineages are TRAJ25, RNU6-735P, and GTF3AP5. Each is linked with TMEM221 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM221-to-partner and partner-to-TMEM221 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (TMEM221→partner) and Y-score (partner→TMEM221) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.