Across TCGA patient cohorts, TMEM215 mutation is significantly associated with the RNA expression of many other genes, with 3,532 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM215-associated genes across cancer lineages are RN7SL209P, FANCC, and MND1. Each is linked with TMEM215 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM215-to-partner and partner-to-TMEM215 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM215→partner) and Y-score (partner→TMEM215) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RN7SL209P →	+0.144	+5.447	<.001	.005	3	3
UCEC	FANCC →	+0.469	+3.032	<.001	<.001	3	3
UCEC	MND1 →	+0.879	+2.643	<.001	<.001	3	3
SKCM	RNU6-895P →	+0.399	+3.877	<.001	.003	3	3
UCEC	CCL4 →	+0.660	+1.673	.003	.003	3	2
UCEC	TUBGCP5 →	+0.356	+2.295	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,532 associations by consensus.

Exploration

TMEM215 survival (RNA) · tumor vs normal (RNA) · all TMEM215 data types