Across TCGA pan-cancer cohorts, TMEM213 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TMEM213 data layer compared with 21 for mass-spec protein.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TMEM213 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TMEM213 expression acts as an unfavorable survival marker.
BLCA are the cancer types where TMEM213 Mutation most reproducibly stratifies survival.