Across TCGA patient cohorts, TMEM213 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TMEM213-associated genes across cancer lineages are CTBP2P9, SEBOX, and MIR6858. Each is linked with TMEM213 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM213-to-partner and partner-to-TMEM213 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM213→partner) and Y-score (partner→TMEM213) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CTBP2P9 →	+0.080	+6.080	<.001	.002	3	1
UCEC	SEBOX →	+0.118	+3.302	.001	.009	3	1
UCEC	MIR6858 →	+1.274	+3.652	<.001	.008	3	1
UCEC	RNU6-633P →	+0.675	+3.278	<.001	.005	3	1
UCEC	RNU2-63P →	+0.642	+3.958	.009	.002	3	1
UCEC	SRMP3 →	+0.274	+3.838	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

TMEM213 survival (RNA) · tumor vs normal (RNA) · all TMEM213 data types