Across TCGA patient cohorts, TMEM212 protein abundance is significantly associated with the RNA expression of many other genes, with 1,677 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM212-associated genes across cancer lineages are HMOX1, RUBCNL, and ADGRE2. Each is linked with TMEM212 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM212-to-partner and partner-to-TMEM212 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM212→partner) and Y-score (partner→TMEM212) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HMOX1 →	+0.624	+0.948	<.001	.008	3	2
LSCC	RUBCNL →	+0.433	+1.050	.002	<.001	3	2
LUAD	ADGRE2 →	+0.772	+1.311	<.001	<.001	3	2
LSCC	APOE →	+0.923	+0.974	<.001	.002	3	2
LUAD	LILRB2 →	+0.709	+1.234	<.001	.001	3	2
LSCC	ITGAX →	+0.946	+1.454	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,677 associations by consensus.

Exploration

TMEM212 survival (RNA) · tumor vs normal (RNA) · all TMEM212 data types