TMEM212-IT1

Across TCGA patient cohorts, TMEM212-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,710 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TMEM212-IT1-associated GO terms across cancer lineages are Negative regulation of endocytosis, mRNA transport, and Establishment of RNA localization. Each is linked with TMEM212-IT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM212-IT1-to-partner and partner-to-TMEM212-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of endocytosis grouped by TMEM212-IT1-low versus TMEM212-IT1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM212-IT1→partner) and Y-score (partner→TMEM212-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of endocytosis →	+0.083	+0.079	<.001	<.001	3	6
STAD	mRNA transport →	+0.128	+0.087	<.001	<.001	3	5
STAD	Establishment of RNA localization →	+0.127	+0.084	<.001	<.001	3	5
STAD	tRNA metabolic process →	+0.114	+0.092	<.001	<.001	3	5
STAD	RNA localization →	+0.131	+0.085	<.001	<.001	3	5
STAD	Organic acid catabolic process →	+0.069	+0.094	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,710 associations by consensus.

Negative regulation of endocytosis by TMEM212-IT1 expression — STAD

Explore this box plot interactively →