TMEM212-AS1

Across TCGA pan-cancer cohorts, TMEM212-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated TMEM212-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TMEM212-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TMEM212-AS1 expression acts as an unfavorable survival marker, although some lineages such as LAML and BRCA show a favorable association.

KIRC, KICH, and ACC are the cancer types where TMEM212-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.743	0.894	.014	90	view →
KICH	OS	Tertile	II,III,IV	0.161	0.827	.004	54	view →
ACC	OS	Tertile	All	0.285	0.809	.001	45	view →
LAML	DFS	Tertile	All	0.603	0.385	.007	36	view →
UCEC	OS	Tertile	III,IV	0.353	0.618	.016	30	view →
LUAD	DFS	Tertile	IV	0.047	0.565	<.001	24	view →
MESO	OS	Tertile	IV	0.188	0.622	.021	18	view →
ESCA	DFS	Tertile	II,III,IV	0.131	0.776	.043	15	view →
THCA	OS	Tertile	III,IV	0.196	0.888	.015	12	view →
DLBC	OS	Tertile	All	0.613	0.945	.049	9	view →
READ	DFS	Tertile	III,IV	0.269	0.744	.025	9	view →
BRCA	DFS	Tertile	II,III,IV	0.979	0.883	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

TMEM212-AS1–KIRC (OS)

Open the KIRC breakdown →