TMEM212-AS1

Across TCGA pan-cancer cohorts, TMEM212-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TMEM212-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TMEM212-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMEM212-AS1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

KIRC, HNSC, and LUSC are the cancer types where TMEM212-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMEM212-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.050	.012	6	view →
HNSC	Male	III,IV	+0.038	.037	2	view →
LUSC	All	II,III,IV	−0.065	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

TMEM212-AS1–KIRC

Open the KIRC breakdown →