TMEM209

Across TCGA patient cohorts, TMEM209 protein abundance is significantly associated with the RNA expression of many other genes, with 14,881 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM209-associated genes across cancer lineages are PLCL2, FAM110D, and PPP1R16B. Each is linked with TMEM209 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM209-to-partner and partner-to-TMEM209 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM209 versus PLCL2 in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM209→partner) and Y-score (partner→TMEM209) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PLCL2 →	-0.928	-0.360	<.001	<.001	3	6
CCRCC	FAM110D →	-0.821	-0.216	<.001	<.001	3	6
GBM	PPP1R16B →	-1.539	-0.233	<.001	<.001	3	5
GBM	TMEM273 →	-0.743	-0.204	<.001	<.001	3	5
CCRCC	PTPRB →	-0.950	-0.212	<.001	<.001	3	5
HNSC	TNXB →	-1.243	-0.289	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,881 associations by consensus.

TMEM209 vs PLCL2 — UCEC

Explore this scatter interactively →