Across TCGA patient cohorts, TMEM207 mutation is significantly associated with the RNA expression of many other genes, with 1,033 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM207-associated genes across cancer lineages are OR4C46, RNU5A-4P, and PSMC2P2. Each is linked with TMEM207 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM207-to-partner and partner-to-TMEM207 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM207→partner) and Y-score (partner→TMEM207) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR4C46 →	+0.179	+7.741	<.001	.009	3	2
LIHC	RNU5A-4P →	+0.447	+5.186	<.001	.007	3	1
LIHC	PSMC2P2 →	+0.064	+5.758	<.001	.003	3	1
BLCA	SNORD114-4 →	+0.440	+5.444	<.001	.002	3	1
UCEC	CHEK1 →	+0.707	+3.343	.001	.005	3	1
UCEC	HIRIP3 →	+0.449	+3.354	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,033 associations by consensus.

Exploration

TMEM207 survival (RNA) · tumor vs normal (RNA) · all TMEM207 data types