TMEM205

Across TCGA patient cohorts, TMEM205 protein abundance is significantly associated with the RNA expression of many other genes, with 10,134 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM205-associated genes across cancer lineages are TTL, CCM2, and UCK2. Each is linked with TMEM205 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM205-to-partner and partner-to-TMEM205 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM205 versus TTL in LSCC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM205→partner) and Y-score (partner→TMEM205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TTL →	-0.322	-0.268	.004	.005	3	5
OV	CCM2 →	-0.410	-0.609	<.001	.001	3	4
UCEC	UCK2 →	-0.645	-0.559	.002	.003	2	5
UCEC	SMC3 →	-0.625	-0.789	<.001	<.001	3	4
OV	SWSAP1 →	+0.722	+0.760	<.001	<.001	3	4
UCEC	XRCC5 →	-0.573	-0.633	.006	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,134 associations by consensus.

TMEM205 vs TTL — LSCC

Explore this scatter interactively →