TMEM205

Across TCGA cell cohorts, TMEM205 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,669 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM205-associated GO terms across cancer lineages are Nephron tubule morphogenesis, Cytosolic small ribosomal subunit assembly, and Small-subunit processome assembly. Each is linked with TMEM205 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM205-to-partner and partner-to-TMEM205 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nephron tubule morphogenesis grouped by TMEM205-low versus TMEM205-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM205→partner) and Y-score (partner→TMEM205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nephron tubule morphogenesis →	-0.054	-0.672	.001	.005	3	7
BREAST	Cytosolic small ribosomal subunit assembly →	-0.067	-0.743	<.001	.001	3	6
BREAST	Small-subunit processome assembly →	-0.067	-0.743	<.001	.001	3	6
URINARY_TRACT	Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	-0.099	-1.514	.001	<.001	3	6
LUNG_NSCLC_LUAD	Regulation of connective tissue replacement →	-0.122	-0.743	<.001	.001	3	6
BREAST	Mitotic chromosome movement towards spindle pole →	-0.122	-0.821	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,669 associations by consensus.

Nephron tubule morphogenesis by TMEM205 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →