TMEM205

Across TCGA cell cohorts, TMEM205 mutation is significantly associated with the mutation status of many other genes, with 1,294 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM205-associated genes across cancer lineages are EEF2K, TRIP4, and PANX2. Each is linked with TMEM205 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM205-to-partner and partner-to-TMEM205 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EEF2K grouped by TMEM205-low versus TMEM205-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM205→partner) and Y-score (partner→TMEM205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EEF2K →	+3.894	+5.247	.001	.001	1	2
BLOOD_Leukemia	TRIP4 →	+4.309	+4.560	.007	.007	1	2
BLOOD_Leukemia	PANX2 →	+3.479	+4.932	.002	.002	1	2
BLOOD_Leukemia	UBTF →	+3.894	+5.247	.001	.001	1	2
BLOOD_Leukemia	PSMC3IP →	+6.479	+6.479	<.001	<.001	1	2
BLOOD_Leukemia	TMEM129 →	+4.309	+4.560	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,294 associations by consensus.

EEF2K by TMEM205 expression — BLOOD_Leukemia

Explore this box plot interactively →