TMEM196

Across TCGA patient cohorts, TMEM196 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,437 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM196-associated proteins across cancer lineages are PURA, UPP1, and CERT1. Each is linked with TMEM196 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM196-to-partner and partner-to-TMEM196 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM196 versus PURA in UCEC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM196→partner) and Y-score (partner→TMEM196) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PURA →	+0.300	+0.395	<.001	.008	3	4
GBM	UPP1 →	-0.702	-0.487	<.001	.006	3	4
UCEC	CERT1 →	-0.373	-0.656	<.001	<.001	3	4
GBM	STXBP6 →	+0.724	+0.527	<.001	<.001	3	3
UCEC	PPP1R21 →	+0.180	+0.549	<.001	.002	3	3
LSCC	VDAC1_S104 →	-0.408	-0.158	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,437 associations by consensus.

TMEM196 vs PURA — UCEC

Explore this scatter interactively →