TMEM192

Across TCGA cell cohorts, TMEM192 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,331 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM192-associated GO terms across cancer lineages are Ribosomal subunit export from nucleus, Ribosome localization, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with TMEM192 in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM192-to-partner and partner-to-TMEM192 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal subunit export from nucleus grouped by TMEM192-low versus TMEM192-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM192→partner) and Y-score (partner→TMEM192) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Ribosomal subunit export from nucleus →	+0.113	+0.930	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Ribosome localization →	+0.113	+0.930	<.001	<.001	3	12
BLOOD_Myeloma	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.063	+0.802	.002	.005	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of formation of translation preinitiation complex →	+0.084	+0.869	.003	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of formation of translation preinitiation complex →	+0.084	+0.869	.003	.001	3	9
SKIN	Melanosome organization →	+0.132	+0.739	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,331 associations by consensus.

Ribosomal subunit export from nucleus by TMEM192 expression — UPPER_AERODIGESTIVE_TRACT

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