Across TCGA patient cohorts, TMEM191C RNA expression is significantly associated with the protein abundance of many other proteins, with 11,387 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM191C-associated proteins across cancer lineages are MAP4K1_S326, RANBP1, and SPINDOC_S308. Each is linked with TMEM191C in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM191C-to-partner and partner-to-TMEM191C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM191C→partner) and Y-score (partner→TMEM191C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MAP4K1_S326 →	-0.851	-0.242	<.001	.007	3	4
LSCC	RANBP1 →	+0.391	+0.189	<.001	<.001	3	4
HNSC	SPINDOC_S308 →	+0.582	+0.191	<.001	<.001	3	4
GBM	CAP1_S275 →	-0.598	-0.213	.007	.003	3	3
LSCC	ADNP →	+0.356	+0.245	<.001	<.001	3	3
LSCC	CKAP4_S26 →	-0.594	-0.166	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,387 associations by consensus.

Exploration

TMEM191C survival (RNA) · tumor vs normal (RNA) · all TMEM191C data types