TMEM190

Across TCGA patient cohorts, TMEM190 RNA expression is significantly associated with the mutation status of many other genes, with 7,816 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM190-associated genes across cancer lineages are MYH4, MYH7, and MYH2. Each is linked with TMEM190 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM190-to-partner and partner-to-TMEM190 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH4 grouped by TMEM190-low versus TMEM190-high in UCEC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM190→partner) and Y-score (partner→TMEM190) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYH4 →	-2.032	-1.195	<.001	<.001	3	3
UCEC	MYH7 →	-1.719	-1.310	<.001	<.001	3	3
UCEC	MYH2 →	-2.064	-1.198	<.001	<.001	3	3
LUAD	SLIT2 →	-2.807	-0.989	.003	.001	3	3
LUAD	CD163 →	-3.798	-1.178	<.001	.001	3	3
LUAD	DNAH9 →	-1.103	-0.701	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,816 associations by consensus.

MYH4 by TMEM190 expression — UCEC

Explore this box plot interactively →