TMEM19

Across TCGA patient cohorts, TMEM19 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,546 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM19-associated proteins across cancer lineages are CAND1, AHNAK_T4564, and USP5. Each is linked with TMEM19 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM19-to-partner and partner-to-TMEM19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM19 versus CAND1 in OV, with a Pearson correlation of 0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM19→partner) and Y-score (partner→TMEM19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CAND1 →	+0.315	+0.486	.007	.004	3	4
CCRCC	AHNAK_T4564 →	+0.906	+0.421	.002	.004	3	4
LUAD	USP5 →	+0.173	+0.257	<.001	.006	3	4
OV	RAB21 →	+0.290	+0.781	.002	<.001	3	3
BRCA	H2AX_Y143 →	-0.740	-0.392	<.001	.002	3	3
BRCA	HNMT →	+0.345	+0.348	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,546 associations by consensus.

TMEM19 vs CAND1 — OV

Explore this scatter interactively →