TMEM19

Across TCGA cell cohorts, TMEM19 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,363 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM19-associated GO terms across cancer lineages are Mitotic nuclear division, Mitotic G2/M transition checkpoint, and Regulation of cell cycle checkpoint. Each is linked with TMEM19 in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM19-to-partner and partner-to-TMEM19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic nuclear division grouped by TMEM19-low versus TMEM19-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM19→partner) and Y-score (partner→TMEM19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitotic nuclear division →	+0.110	+1.090	<.001	<.001	3	14
OESOPHAGUS	Mitotic G2/M transition checkpoint →	+0.098	+1.194	<.001	<.001	3	14
BREAST	Regulation of cell cycle checkpoint →	+0.114	+1.586	<.001	<.001	3	13
OESOPHAGUS	Positive regulation of mitotic cytokinesis →	+0.130	+1.019	.002	.003	3	13
OESOPHAGUS	Positive regulation of chromosome condensation →	+0.227	+1.176	<.001	.001	3	13
PANCREAS	Immunoglobulin heavy chain V-D-J recombination →	+0.185	+0.994	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,363 associations by consensus.

Mitotic nuclear division by TMEM19 expression — OESOPHAGUS

Explore this box plot interactively →